Pallas Health vs He & She MD: comparing prices and support
Pallas Health vs He & She MD: both sell clinician-supervised GLP-1 plans online, but they differ in pricing structure, medication routes and bundled support. Early verdict: choose Pallas if you want one intake offering both brand-name pens and per-patient compounded preparations with a stated first-month price; choose He & She MD if you prioritize a built-in coaching app and a six-month introductory rate with clinician messaging.
Pricing model and renewal cadence
Pallas Health lists compounded semaglutide at $139 for the first month, then $597 every 12 weeks, a $199/month average, and compounded tirzepatide $179 first month then $897 every 12 weeks ($299/mo avg). Pallas also offers brand-name Wegovy®, Ozempic®, Zepbound® and Mounjaro® as cash-pay plans at listed monthly cash prices. Pallas prices compounded plans by medication so titration does not raise the plan price. Pallas is cash-pay only and does not bill insurance.
He & She MD pricing and intro offers
He & She MD advertises semaglutide injections starting at $139/month and oral semaglutide or tirzepatide injections at $199/month as six-month introductory rates that renew higher; the site notes those are six-month terms and that the promo rates renew at standard six-month prices after the introductory term.
Medication options and clinician selection
Pallas presents both routes from one intake: a US-licensed clinician reviews your history and may choose FDA-approved brand-name GLP-1s or clinician-personalized compounded semaglutide or tirzepatide prepared in the USA when a brand medication is not the right fit. Pallas says it does not manufacture or compound medication; compounding is done by US-licensed compounding pharmacies. He & She MD sells compounded semaglutide injection, oral semaglutide and tirzepatide injection, with meds produced in USP-compliant, state-regulated pharmacies but not reviewed by the FDA for safety, efficacy or quality.
Support and care model
Pallas includes provider care, ongoing check-ins and care-team messaging in one all-in plan price, with no membership fee; it is 100% online and asynchronous in most states, with a video visit required in seven states plus Washington, D.C. Pallas notes care-team hours are weekdays 9 AM–5 PM ET and no emergency services are offered.
He & She MD bundles a coaching app with 1:1 clinician messaging, GLP-1-specific coaching and progress tracking at no extra cost. The program emphasizes coaching and clinician access built into the plan rather than sold separately. He & She MD advertises a named, dual board-certified obesity-medicine Chief Medical Officer and quick intakes.
Regulatory and labelling notes
Both providers state that compounded medications are not reviewed by the FDA for safety, effectiveness or quality. Pallas explicitly notes that compounded medications are not FDA-approved and are not generic versions of brand-name drugs and that the medication you receive may differ in appearance from any product shown on the site. He & She MD notes medications are produced in USP-compliant, state-regulated pharmacies but not reviewed by the FDA.
Direct comparison table
| Criteria | Pallas Health | He & She MD |
|---|---|---|
| Starting price (compounded semaglutide) | $139 first month, then $597/12 weeks ($199/mo avg) | $139/month intro for six months (then renews higher) |
| Tirzepatide pricing (compounded) | $179 first month, then $897/12 weeks ($299/mo avg) | Tirzepatide injection at $199/month intro (six-month term) |
| Medication routes offered | Brand-name pens and compounded semaglutide or tirzepatide | Compounded semaglutide injection, oral semaglutide, tirzepatide injection |
| Care and support | Provider care, ongoing check-ins and messaging included; asynchronous in most states | Coaching app with 1:1 clinician messaging and progress tracking included |
| Billing cadence | Compounded plans billed per 12-week renewal; cash-pay only | Structured as six-month introductory terms that renew at higher six-month prices |
| Regulatory note | Compounded meds not FDA-approved; prepared by US compounding pharmacies | Compounded meds produced in USP-compliant, state-regulated pharmacies; not reviewed by FDA |
Which differences matter most
1) Pricing cadence. Pallas uses an initial first-month price then a 12-week renewal schedule with an average monthly figure disclosed. He & She MD uses six-month introductory rates that renew at higher six-month prices. 2) Combined brand and compounded access. Pallas explicitly offers brand-name FDA-approved pens or a clinician-chosen compounded preparation from the same intake. He & She MD focuses on compounded injectable and oral formats. 3) Support delivery. He & She MD emphasizes a coaching app with 1:1 clinician messaging and tracking bundled in; Pallas emphasizes clinician review and asynchronous online care with included check-ins and messaging and notes limited care-team hours. 4) Regulatory framing. Both note that compounded products are not reviewed by the FDA, and each describes the compounding or pharmacy oversight differently.
Pallas Health vs He & She MD and the primary keyword
When evaluating Pallas Health vs He & She MD, use the primary keyword considerations above: pricing cadence, whether you want brand-name options versus only compounded formats, and whether bundled coaching or asynchronous clinician review matters more to you.
Choose one if…
Choose Pallas Health if you want a single intake that lets a US-licensed clinician pick between FDA-approved brand-name pens and a clinician-personalized compounded preparation, prefer a first-month compounded price of $139 and a plan that bills compounded plans every 12 weeks with provider care included.
Choose He & She MD if you want a program that bundles a coaching app with 1:1 clinician messaging and progress tracking and are willing to accept six-month introductory rates that renew at a higher standard six-month price.
Neither provider bills insurance; both note compounded medications are not reviewed by the FDA. If additional specific clinical details or state availability are needed, those are not supplied here and should be confirmed with each provider directly.