Enhance MD vs Refills: Semaglutide and Pricing Compared
Enhance MD vs Refills comes down to entry price, compound choices, and support options. Early verdict: Enhance MD is the lowest-cost entry point for semaglutide and tirzepatide first months, while Refills emphasizes a $99/month flat plan with free shipping and 24/7 concierge.
Start with Enhance MD from $49 first month
Quick comparison: pricing, compounds, and support
This direct comparison uses only supplied facts. Both providers offer compounded GLP-1 products and flat-rate pricing that stays the same at every dose, but they differ on starting prices, compound lineup, and patient support features.
What sets them apart
- Starting price: Enhance MD lists semaglutide from $49 first month and tirzepatide from $99 first month. Refills lists GLP-1 from $99/month (~$5/day) and tirzepatide from $159/mo.
- Compound options: Enhance MD highlights both semaglutide and tirzepatide on one platform. Refills offers semaglutide, tirzepatide, and mentions a GIP plus GLP-1 dual agonist available.
- Support and shipping: Refills advertises free discreet shipping and 24/7 health concierge. Enhance MD emphasizes clinician-directed care and a large treated patient base of 10,000+.
- Billing and plan features: Refills states month-to-month plans that can be canceled anytime with no contracts. Enhance MD operates on a direct-pay model and does not bill insurance.
- Regulatory note: Both providers state compounded medications are not FDA-approved and are not reviewed by FDA for safety, effectiveness or quality.
Side-by-side table
| Criteria | Enhance MD | Refills |
|---|---|---|
| Starting price | Semaglutide from $49 first month; Tirzepatide from $99 first month | GLP-1 from $99/month (~$5/day); Tirzepatide $159/mo |
| Flat pricing at every dose | Flat-rate pricing: same price at every dose, no escalation | Flat pricing: same price at every dosage, no titration upcharges |
| Compound options | Semaglutide and tirzepatide on one platform | Semaglutide, tirzepatide, and GIP+GLP-1 dual agonist available |
| Shipping and support | Not specified as free shipping; clinician-directed care; 10,000+ patients treated | Free discreet shipping; 24/7 health concierge; express shipping claimed |
| Plan flexibility | Direct-pay model; does not bill insurance | Month-to-month; cancel anytime; no contracts or cancellation fees |
| Regulatory note | Compounded medications are not FDA-approved and are not reviewed by FDA | Compounded drug products are not FDA-approved and are not reviewed by FDA |
Pricing and introductory offers
Enhance MD advertises the cheapest first-month prices for both compounds: semaglutide from $49 and tirzepatide from $99 for the first month, with a flat-rate model thereafter. Refills advertises a single flat-price starting at $99/month for GLP-1 and lists tirzepatide at $159/mo. Both sources note compounded medications are not FDA-approved.
See Refills $99/mo plan and shipping
Compounds, clinical review, and pharmacy details
Enhance MD highlights availability of both semaglutide and tirzepatide on one platform and reports treating more than 10,000 patients. Refills notes semaglutide and tirzepatide availability plus a GIP plus GLP-1 dual agonist, and states it dispenses from U.S. pharmacies with partner clinicians reviewing intakes.
Support, shipping, and convenience
Refills advertises free discreet shipping, 24/7 health concierge support, and month-to-month plans with simple refill steps and clinician consultations at no extra cost. Enhance MD emphasizes clinician-directed metabolic care and flat-rate pricing but does not claim free shipping in the captured evidence.
Explore Enhance MD clinician-directed programs
Risks, regulation, and limitations
Both providers explicitly state compounded medications are not approved or evaluated by the FDA for safety, effectiveness, or quality. Enhance MD notes treatment is available only when a licensed clinician determines it is medically appropriate. Refills also requires a prescription and clinician review of intake information.
Final verdict and who should choose which
Enhance MD vs Refills: choose based on entry cost, compound needs, and support preferences. Enhance MD is the lowest-cost entry for first-month semaglutide and tirzepatide pricing and offers both compounds on one platform. Refills offers a clear $99/month flat plan with free shipping, round-the-clock concierge support, and month-to-month flexibility.
Compare Refills plans and support
Choose Enhance MD if…
you prioritize the lowest advertised first-month price for semaglutide or tirzepatide and want both compounds available on one clinician-directed platform with flat-rate dosing.
Choose Refills if…
you prefer a $99/month flat plan with free discreet shipping, 24/7 health concierge, and month-to-month cancellation flexibility.
Comparison keyword: Enhance MD vs Refills